Tropical Disease Initiative Releases Kernel

No, really:

There is an urgent need for identifying new targets for drug discovery. This urgency is even more relevant for infectious diseases affecting third-world countries, which have been historically neglected by the pharmaceutical industry. For example, only ~10% of the R&D resources have been spent on illnesses that represent the 90% of the total disease burden in the world (Munos 2006), which translates in that just ~1% of newly developed drugs are for tropical diseases (Maurer et al. 2004).

At the beginning of the 90s, an initial Linux kernel conceived and created by Linus Torvalds paved the way for a wealth of open and free software programs and operating systems. Here we introduce what we believe can be regarded as an initial kernel for drug discovery with the hope that it will sparkle new ways for developing drugs against organisms that cause tropical diseases. The TDI kernel (v1.0) includes 297 potential drug targets against the 10 selected genomes and is freely and publicly accessible in a World Wide Web server, which was developed with Web2.0 tools for easy dissemination of the deposited data.

It's amazing how metaphors can spread.

You can browser the kernel - *their* kernel - here.

It's *Not* The 15th Birthday of Linux – and Why That Matters

Last week, I wondered whether I'd gone back in time. Everywhere I went online – on news sites, blogs and Twitter – people were celebrating the 15th birthday of Linux, it seemed. “How is this possible?” I asked myself. “Since Linux was started in 1991, that must mean we are in 2006: have I fallen through a wormhole into the past?”

On Linux Journal.

Follow me on Twitter @glynmoody

Linus Gets Misty-Eyed Over the Sinclair QL

Apparently the Sinclair QL (remember the microdrives?) turned 25 yesterday (or thereabouts). One rather famous former owner was Linus; to begin with, he seems unimpressed by this historic moment:

when somebody sends me an email saying that the Sinclair QL turned 25 years old yesterday, and that I should mention it on my blog, I just went "hmm". Because while I had one and loved it, I have to say that I was so much happier with the PC I ended up replacing it with, and decided that I'll never use an odd-ball machine ever again.

But once you've leapt the Quantum Leap, you're never the same again, as Linus finally admits:

the email from Urs König (aka cowo) did end up festering in my mind and brought back fond memories. So here we are, twenty five years and one day later, and I'm writing a shout-out to the QL anyway. It was odd, and it was flaky to the point of being the only machine I had to do hardware surgery on to make stable and useful, but I guess I was at an impressionable age. And while I don't think there were many QL's that ever made it outside Britain, it was an interesting machine for its time.

I'm sure that made Sir Clive's day.

Linus Plays Prince of Persia - Again

Most people in the free software world know that before he wrote Linux, Linus was using the Minix operating system. To run it, he had to acquire his first "proper" PC - his main machine until then was the Sinclair QL (remember that?). As he told me a few years ago, the PC arrived early in 1991....

On Open Enterprise blog.

Alan Cox and the End of an Era

In the beginning, free software was an activity conducted on the margins - using spare time on a university's computers, or the result of lonely bedroom hacking. One of the key moments in the evolution of free software was when hackers began to get jobs - often quite remunerative jobs - with one of the new open source companies that sprang up in the late 1990s. For more or less the first time, coders could make a good salary doing what they loved, and businesses could be successful paying them to write code that would be given away.

On Open Enterprise blog.

Why Free Software is a Con-Trick

A number of sites have noted this interesting study of a particular kind of con-trick, known as "The pigeon drop". What really caught my attention was the following:

The key to a con is not that you trust the conman, but that he shows he trusts you. Conmen ply their trade by appearing fragile or needing help, by seeming vulnerable. Because of THOMAS, the human brain makes us feel good when we help others--this is the basis for attachment to family and friends and cooperation with strangers. "I need your help" is a potent stimulus for action.

Now, how does free software generally operate? It begins with a call for *help* - which means that it elicits the same deep human response as the con-trick described in the original post.

Here are two classics of the free software pigeon-drop con-trick genre, one from RMS:

Starting this Thanksgiving I am going to write a complete Unix-compatible software system called GNU (for Gnu's Not Unix), and give it away free(1) to everyone who can use it. Contributions of time, money, programs and equipment are greatly needed.

The other from Linus:

Hello everybody out there using minix -

I'm doing a (free) operating system (just a hobby, won't be big and professional like gnu) for 386(486) AT clones. This has been brewing since april, and is starting to get ready. I'd like any feedback on things people like/dislike in minix, as my OS resembles it somewhat (same physical layout of the file-system (due to practical reasons) among other things).

This is why proprietary software will never be able to beat free software: because the latter always brings with it an implicit cry for help, rather than simply offering us a cold and clinical business deal, it triggers the release of a powerful neurochemical that actually makes us feel good when we respond to that appeal. It turns out that it's altruism, not greed, that is good.

Linus Up Close and Personal

Here's a brace of videos from the recent Linux Kernel Summit. Human nature being what it is, most interest will probably focus on the interview with Linus.

Truth to tell, there's nothing really dramatic there, but the video's definitely of interest because it's one of the highest quality offerings I've seen: if you've ever wondered what Linus *really* looks and sounds like, this is your chance.

The Real Story Behind GNU/Linux

If the prospect of another week stretching out before you is getting you down, I've got good news. There's a post about GNU/Linux that is guaranteed to bring a smile to your face. It's a real stonker - try this for a start....

On Open Enterprise blog.

Open Source Business Does Not Scale

At first sight, the findings of The 451 Group’s latest CAOS report, “Open Source is Not a Business Model“ might seem to be terrible news for open source....

On Open Enterprise blog.

Linus and the Art of the Kernel Release

In case you missed it, something of truly global importance happened last week. No, not the collapse of capitalism as we know it, something much more profound: Linus started a blog. His first post suggested that it won't be of much interest to the enterprise open source world, since it's really a *personal* blog....

On Open Enterprise blog.

Linus Has a Blog???!?

The end of civilisation as we know it is obviously closer than I thought.... (Via DaveM.)

Get Real, People: Get *Real* People

I'm not a big fan of top “n” lists. They generally lack any kind of metric, and end up with bizarre compromise choices. This “Top Agenda Setters 2008”, supposedly about “the top 50 most influential individuals in the worldwide technology and IT industries”, is no exception....

On Open Enterprise blog.

You, Too, Can Be a Kernel Hacker

On Open Enterprise blog.

Git Gets Down to Business

On Open Enterprise blog.

Linus on the Desktop

On Open Enterprise blog.

Vista's Problem: Microsoft Does Not Scale

It is deeply ironic that once upon a time Linux - and Linus - was taxed with an inability to scale. Today, though, when Linux is running everything from most of the world's supercomputers to the new class of sub-laptops like the Asus EEE PC and increasing numbers of mobile phones, it is Microsoft that finds itself unable to scale its development methodology to handle this range. Indeed, it can't even produce a decent desktop system, as the whole Vista fiasco demonstrates.

But the issue of scaling goes much deeper, as this short but insightful post indicates:

The world has been scaling radically since the Web first came on the scene. But the success of large, open-ended collaborations -- a robust operating system, a comprehensive encyclopedia, some "crowd-sourced" investigative journalism projects -- now is not only undeniable, but is beginning to shape expectations. This year, managers are going to have to pay attention.

Moreover, it points out exactly why scaling is important - and it turns out to be precisely the same reason that open source works so well (surprise, surprise):

The scaling is due to the basic elements in the Web equation: Lots of people, bazillions of pieces of information, and gigabazillions of links among them all. As more of the market, more of the supply chain, and more of the employees spend more of their time online, the scaled world of the Web begins to set the agenda for the little ol' real world.

Linus Says It's In Our DNA

Simon Willison has picked up a nice quotation from Linus he made a few years back, but what really interests me are some other things he said in the same post:

think about how you and me actually came about - not through any complex design.

Right. "sheer luck".

Well, sheer luck, AND:
- free availability and _crosspollination_ through sharing of "source code", although biologists call it DNA.
- a rather unforgiving user environment, that happily replaces bad versions of us with better working versions and thus culls the herd (biologists often call this "survival of the fittest")
- massive undirected parallel development ("trial and error")

In other words, the open source methodology is hard-wired into us - right down at the level of DNA.

Larry Sanger's Question

Larry Sanger has a question about Citizendium:

Suppose we grow to Wikipedian size. This is possible, however probable you think it might be.

Suppose, also, that, because we are of that size, we have the participation of a sizable portion of all the leading intellectuals of the world, in every field–and so, there are hundreds of thousands, if not millions, of approved articles. These are all long, complete with many links, bibliography, etc., etc.–all the subpage stuff. It’s reference utopia. Far better than Wikipedia has any hope of becoming.

Here’s the question, then. If we use a license that permits commercial reuse–CC-by-sa or GFDL–then every major media company in the world could, and probably would, use CZ content. Do you favor a license that allows CBS, Fox, the New York Times, English tabloids, Chinese propaganda sheets, Yahoo!, Google, and all sorts of giant new media companies to come, to use our content? Without compensation?

That's the question that Linus faced over a decade ago when he decided to adopt the GNU GPL instead of the earlier one that forbade any kind of money changing hands. And as Linus has said many times, choosing the GNU GPL was one of the best decisions he ever made, because it has widened support for Linux enormously, and as a result has driven its development even faster.

There's your answer, Larry....

From Rebel Code to Codi Rebel

And now, the moment you've all been waiting for: Rebel Code....in Catalan:

Una història apassionant que ens explica com un grup d'inconformistes desafià les grans empreses i va produir una revolució inesperada en el món dels ordinadors. En 1991 un jove estudiant, Linus Torvalds, va comprar un ordinador personal i es va plantejar l'elaboració d'un nou programari. Tot va començar gairebé com un joc, com un hobby, però en pocs anys, i amb l'ajuda d'un grup d'amics i col·laboradors connectats a través de la xarxa, Torvalds desenvolupà un sistema operatiu que esdevingué un veritable repte per a Microsoft. El programari GNU/Linux és utilitzat avui per milions de persones. I la qüestió que més desassossec provoca entre els grans gegants de la informàtica és que el seu ús és lliure, no costa diners. En aquest relat ple d'anècdotes i d'històries reveladores, Glyn Moody exposa de manera clara i accessible com es va desenvolupar aquesta lluita entre David i Goliat protagonitzada per Linux, bo i situant-la en el context més ampli de la història del moviment en favor del programari lliure. Alhora mostra tot el que es pot aconseguir quan la creativitat i la cooperació intel·lectual es posen per damunt del simple benefici econòmic. Glyn Moody s'ha ocupat de Linux gairebé des del moment de la seua elaboració.

Couldn't have put it better myself.

Update: A here's a word from the translators.

SCO Long, and Thanks for All the Fish

One of the many pleasant knock-on effects of SCO's deliquescence has been some long-overdue crow-eating by high-profile critics of the open source position during that saga. Since I have rigorously vegetarian tendencies when it comes to partaking of that particular dish, I have to admire the, er, guts of Daniel Lyons, who has publicly swallowed his pride and admitted his errors (although, sadly, his potshots at "freetards" in his otherwise wonderful Fake Steve Jobs blog now stick in my craw, for some reason....)

Rob Enderle's case here is more complex. He has written a long and fascinating tale of how he came to do and say what he did and said, but ultimately refuses to apologise for either ("Dan Lyons, me and no apology ). For me, the key paragraph is the following:

Unlike Dan Lyons, who has recently said he was tricked by SCO, I was tricked both by SCO and some Linux supporters who, unintentionally through their nasty behavior and threats, made me see them as the criminals. Nothing I had done gave these people the right to attack my livelihood, threaten my life or the lives of my family, and I still view the folks who engaged in such behavior as criminals.

I too thoroughly repudiate those who, while claiming to be part of the open source community, made any such threats, which were unjustified and unforgivable. But I don't think the word "tricked" is appropriate here. These people did not "trick" Enderle into believing them to be sad sacks: they truly were. But that had nothing to do with the merits of SCO's case.

Aside from SCO's trickery, Enderle made an error of judgment in not believing people like Linus when he said there was no infringing code. The point is, if you examine Linus' track-record - to say nothing of his coding - it was simply inconceivable that large chunks of code had been filched. It was (just about) possible that small parts had been sneaked in by some less-than-scrupulous coders, but given the level of scrutiny the code undergoes, even that was highly unlikely.

Ultimately, it comes down to the fundamental difference between free software and black-box code: one is open - and can be examined by anyone, without signing NDAs - the other is not. The presumption should always be, then, that the former, unlike the latter, has nothing to hide, because it has nowhere to hide it.

Update: ESR says much the same, though with rather more force...