It's a Dog's Life

One of the fascinating things that I learned when I was writing Digital Code of Life is that many diseases - such as obesity, heart disease, diabetes, certain kinds of cancers and neurodegenerative disorders - are not commonly found in the great apes. As I put it then:

In a sense, the human genome has evolved certain advantageous characteristics so quickly that it has not been debugged properly. The major diseases afflicting humans are the outstanding faulty modules in genomic software that Nature was unable to fix in the time since humans evolved as a species.

Another extraordinary fact is that dogs are even more susceptible to these same diseases than humans are, and for the same reason: the domestic breeds have arisen so recently, and from limited populations through inbreeding. But if dogs are like us, only more so, then they also hold out the hope that by investigating the root causes of their afflictions we might be able to understand our own better.

I see that further steps in this direction are now being taken:

Melbourne researchers are examining the DNA of dogs in a research project aiming at determining the genetic causes of common pet diseases – and to provide a model for combating diseases such as diabetes and multiple sclerosis in humans.